Comfort and Adaptation to Silicone Hydrogel Lenses for Daily Wear.

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Comfort and Adaptation to Silicone Hydrogel Lenses for Daily Wear. Eye Contact Lens. 2008 Jul;34(4):215-223 Authors: Dumbleton KA, Woods CA, Jones LW, Fonn D OBJECTIVES.: To investigate initial comfort and adaptation of currently successful low oxygen transmissibility soft lens wearers refitted with silicone hydrogel (SH) lenses for daily wear. METHODS.: Fifty-five subjects were enrolled in a subject-masked 5-month clinical trial in which they wore 5 SH lenses in a randomized, crossover design. Comfort, burning, and dryness were rated on scales of 0 to 100 immediately on insertion and the time for lens settling was recorded. Symptoms were then rated at various times, using BlackBerry wireless communication devices (Research in Motion, Waterloo, Canada), during the day for 2 cycles of 2 weeks wear for each lens type. RESULTS.: Comfort immediately on insertion varied between lens types (P=0.002). All lens types were reported by the subjects to have settled within 30 to 45 sec of insertion (P=0.14) and "settled" comfort was greater than comfort immediately on insertion (P