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Can Vitamin D improve your eyesight? Join a QUT study to help find out - HealthCanal.com...

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Vitamin D, huh?
 
Optom Vis Sci. 2011 Mar;88(3):377-82. doi: 10.1097/OPX.0b013e31820b0385.
Blood levels of vitamin D in teens and young adults with myopia.
Mutti DO1, Marks AR.
Author information
  • 1The Ohio State University College of Optometry, Columbus, Ohio 43210-1280, USA. mutti.2@osu.edu
Abstract
PURPOSE:
Longitudinal data suggest that time outdoors may be protective against myopia onset. We evaluated the hypothesis that time outdoors might create differences in circulating levels of vitamin D between myopes and non-myopes.

METHODS:
Subjects provided 200 μl of peripheral blood in addition to survey information about dietary intakes and time spent in indoor or outdoor activity. The 22 subjects ranged in age from 13 to 25 years. Myopes (n = 14) were defined as having at least -0.75 diopter of myopia in each principal meridian and non-myopes (n = 8) had +0.25 diopter or more hyperopia in each principal meridian. Blood level of vitamin D was measured using liquid chromatography/mass spectroscopy.

RESULTS:
Unadjusted blood levels of vitamin D were not significantly different between myopes (13.95 ± 3.75 ng/ml) and non-myopes (16.02 ± 5.11 ng/ml, p = 0.29) nor were the hours spent outdoors (myopes = 12.9 ± 7.8 h; non-myopes = 13.6 ± 5.8 h; p = 0.83). In a multiple regression model, total sugar and folate from food were negatively associated with blood vitamin D, whereas theobromine and calcium were positively associated with blood vitamin D. Myopes had lower levels of blood vitamin D by an average of 3.4 ng/ml compared with non-myopes when adjusted for age and dietary intakes (p = 0.005 for refractive error group, model R = 0.76). Gender, time outdoors, and dietary intake of vitamin D were not significant in this model.

CONCLUSIONS:
The hypothesis that time outdoors might create differences in vitamin D could not be evaluated fully because time outdoors was not significantly related to myopia in this small sample. However, adjusted for differences in the intake of dietary variables, myopes appear to have lower average blood levels of vitamin D than non-myopes. Although consistent with the hypothesis above, replication in a larger sample is needed.

PMID:

21258262

[PubMed - indexed for MEDLINE]
PMCID:

PMC3044787

Free PMC Article
 
The concept of whether Vit D can improve eyesight is reasonable to investigate. I question the methodology here. You would need to have blood work to establish the Vit D levels before and after the study. The 1000 IU dosage is very low. I would suggest 10000 IU/day during the course of the study to achieve a significant increase in serum levels.
The rationale for testing Vit D eye effects is that there is a higher concentration of Vit D receptors in the retina than any other tissue in the body, probably related to the high metabolic rate. It's theorized relationship to myopia development is from potentially strengthening the structural integrity of the sclera.
Ed Melman




ODwire.org NewsBot said:

Can Vitamin D improve your eyesight? Join a QUT study to help find out
HealthCanal.com (press release) (blog)
Chih Huang Yang, a PhD student in QUT's School of Optometry, is hoping to attract 60 men and women to his project before the end of October and is offering $10 gift vouchers as an incentive to those who do sign up. "I am looking for people that are ...

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