1. Welcome to ODwire.org, the largest and longest-running social network for eye care professionals, with over 20,000 ECP members!

    We offer private peer-to-peer discussions, articles, webinars, podcasts & more!

    Our site is free to all Optometrists, OD Students, Opticians, and Ophthalmologists, and practice administrators. Join us!
  2. Dismiss Notice

Macular Degeneration

Discussion in 'General Topics' started by Michael Margaretten, May 11, 2019.

  1. Michael Margaretten

    319
    Messages
    Joined:
    Jul 17, 2001
    School/Org:
    Pennsylvania College of Optometry
    City:
    Hollywood
    State:
    FL
    Personalized 'eye-in-a-dish' models reveal genetic underpinnings of macular degeneration
    Date:
    May 9, 2019
    Source:
    University of California - San Diego
    Summary:
    Using stem cells derived from six people, researchers recapitulated retinal cells in the lab. This 'eye-in-a-dish' model allowed them to identify genetic variants that cause age-related macular degeneration, a common cause of vision loss.
    Share:
    Materials provided by University of California - San Diego. Original written by Heather Buschman, PhD. Note: Content may be edited for style and length.

    Journal Reference:

    1. Erin N. Smith, Agnieszka D'Antonio-Chronowska, William W. Greenwald, Victor Borja, Lana R. Aguiar, Robert Pogue, Hiroko Matsui, Paola Benaglio, Shyamanga Borooah, Matteo D'Antonio, Radha Ayyagari, Kelly A. Frazer. Human iPSC-Derived Retinal Pigment Epithelium: A Model System for Prioritizing and Functionally Characterizing Causal Variants at AMD Risk Loci. Stem Cell Reports, 2019; DOI: 10.1016/j.stemcr.2019.04.012
    Cite This Page:

    University of California - San Diego. "Personalized 'eye-in-a-dish' models reveal genetic underpinnings of macular degeneration." ScienceDaily. ScienceDaily, 9 May 2019. <www.sciencedaily.com/releases/2019/05/190509125155.htm>.