GLP-1s may double risk for development of wet AMD - Healio

Just as an aside (and as a teaser) Dr. Julie Rodman will be giving a talk about the ocular effects of GLP1 analogs at CEwire2026.

More details to follow as the site goes live in a couple of weeks

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Now that Celebes are marketing online doctors and prescribing and the Trump Administration is working to lower the price this is more relevant.
 
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The increase was from 0.1% to 0.2%. So double, but still very small.
The relative risk is incredibly small, since the base was small. I would say for many people the systemic benefits far outweigh the risk, especially if someone is morbidly obese.
 
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The relative risk is incredibly small, since the base was small. I would say for many people the systemic benefits far outweigh the risk, especially if someone is morbidly obese.
Don't you mean absolute risk? The relative risk doubled, the absolute risk is small.
 
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Just as an aside (and as a teaser) Dr. Julie Rodman will be giving a talk about the ocular effects of GLP1 analogs at CEwire2026.

More details to follow as the site goes live in a couple of weeks

-- ad
Just as you Adam predict AI has problems as well as good I believe long term more and more problems and health concerns with emerge from GPL1 drugs. Yes they may help type II diabetics more then hurt but for the general population who take it to be stick figures watch out for those long term effects. You are changing basic function of the GI system " GLP-1, leading to increased insulin secretion, reduced glucagon secretion, delayed gastric emptying, and appetite suppression, thereby improving glycemic control and promoting weight loss."

Sounds good but let's wait a few years and see what may happen
 
Don't you mean absolute risk? The relative risk doubled, the absolute risk is small.
Yup, both are still low, relative to the effects of morbid obesity. Which is what these drugs really should be used for.

Because Steve is correct, the long-term effects of the drugs are unknown. Especially for people who are using them cosmetically [which is the majority of the people taking them, to knock 20 or 30 lbs off] they may get more than they bargained for.

Time will tell ...
 
Just as you Adam predict AI has problems as well as good I believe long term more and more problems and health concerns with emerge from GPL1 drugs. Yes they may help type II diabetics more then hurt but for the general population who take it to be stick figures watch out for those long term effects. You are changing basic function of the GI system " GLP-1, leading to increased insulin secretion, reduced glucagon secretion, delayed gastric emptying, and appetite suppression, thereby improving glycemic control and promoting weight loss."

Sounds good but let's wait a few years and see what may happen
Yet obesity is behind most of the health issues we face as a nation, so obese patients will probably still come out ahead.
 
Yet obesity is behind most of the health issues we face as a nation, so obese patients will probably still come out ahead.
Err even with the cost reductions Trump just put in most people who are obese still can't afford it especially if they are presumably on other meds which I would suspect